KMID : 0359020130460050582
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Korean Journal of Gastrointestinal Endoscopy 2013 Volume.46 No. 5 p.582 ~ p.585
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Gastric Somatostatinoma: An Extremely Rare Cause of Upper Gastrointestinal Bleeding
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Prachayakul Varayu
Aswakul Pitulak Deesomsak Morakod Pongpaibul Ananya
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Abstract
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A 49-year-old woman presented with chronic abdominal discomfort, significant weight loss, and chronic intermittent diarrhea. She suddenly developed massive upper gastrointestinal bleeding and was referred for further treatment. Endoscopy indicated a large mass in the upper gastric body with antral and duodenal bulb involvement. Endosonography showed a large well-defined isoechoic gastric subepithelial mass with multiple intra-abdominal and peripancreatic lymphadenopathy, suspected to be malignant on the basis of fine needle aspiration cytology. The tumor was surgically removed, and histopathology showed typical characteristics of a neuroendocrine tumor. On the basis of immunohistochemical staining, somatostatinoma, a rare neuroendocrine tumor, was diagnosed. Gastrointestinal bleeding is a rare presentation and the stomach is an uncommon tumor location.
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KEYWORD
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Somatostatinoma, Stomach metastasis, Endosonography, Neuroendocrine tumors
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